Gender-specific ischemic tissue tolerance in critically perfused skin
نویسندگان
چکیده
منابع مشابه
Hemoglobin vesicles improve wound healing and tissue survival in critically ischemic skin in mice.
Local hypoxia, as due to trauma, surgery, or arterial occlusive disease, may severely jeopardize the survival of the affected tissue and its wound-healing capacity. Initially developed to replace blood transfusions, artificial oxygen carriers have emerged as oxygen therapeutics in such conditions. The aim of this study was to target primary wound healing and survival in critically ischemic skin...
متن کاملTRANSLATIONAL PHYSIOLOGY Hemoglobin vesicles improve wound healing and tissue survival in critically ischemic skin in mice
Plock JA, Rafatmehr N, Sinovcic D, Schnider J, Sakai H, Tsuchida E, Banic A, Erni D. Hemoglobin vesicles improve wound healing and tissue survival in critically ischemic skin in mice. Am J Physiol Heart Circ Physiol 297: H905–H910, 2009. First published July 2, 2009; doi:10.1152/ajpheart.00430.2009.—Local hypoxia, as due to trauma, surgery, or arterial occlusive disease, may severely jeopardize...
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Most current models of T cell development include a positive selection step in the thymus that occurs when T cells interact with thymic epithelium and a negative selection step after encounters with bone marrow-derived cells. We show here that developing T cells are tolerized when they recognize antigens expressed by thymic epithelium, that the tolerance is tissue specific, and that it can occu...
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Transmural heterogeneity of myocardial metabolism and function are present in the left ventricle under normal and ischemic conditions. To determine if endocardial versus epicardial differences of [Ca2`11 are also present, perfused rat heart studies using indo-1 fluorescence as an index of [Ca2"]i were performed in the left ventricular epicardium and endocardium. Hearts were studied during contr...
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Prostacyclin (PGI2) and some of its major breakdown products (6-keto-PGFi,,, 6-ketoPGEi, and 13,14-dihydro 6,15-diketo-PGFia) were studied in an isolated perfused cat heart preparation during myocardial ischemia. At an infusion rate of 10 ng/g heart weight per minute, PGI2 and the related compounds caused no changes in perfusion pressure, contractile force (CF), the first derivative of the cont...
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ژورنال
عنوان ژورنال: Langenbeck's Archives of Surgery
سال: 2009
ISSN: 1435-2443,1435-2451
DOI: 10.1007/s00423-009-0558-9